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ATTENTION: The purpose of this website is to produce hypotheses that can explain the causes of possible diseases based on the cause of alopecia, which is addressed with a multidisciplinary and non-traditional approach.
This is not an approved method or hypothesis. It is not a recommendation. It is not suitable for personal action and is not designed for personal action. Do not make any assumptions or applications without consulting health professionals. No responsibility is assumed.
What Is The Human Topologıcal Hypothesıs?
What Is The Human Topologıcal Hypothesıs?
Human skin, regardless of age or ethnicity, exhibits different strengths and characteristics at every layer and in each of its components. Although we acknowledge that human skin is a large organ, when examined locally, it is composed of microstructures. Components such as hair shafts, which possess high tensile strength and elasticity, do not present a problem as they emerge outward from the body. In fact, hair loss is most often perceived as a cosmetic issue. It is thought that the immune system attacks hair follicles due to genetic or erroneous signaling.
Humans have a large number of hair shafts on their scalp, and the strength and properties of these hair shafts have been the subject of numerous studies. The skin covers and protects the skeletal and connective tissue systems, adapting itself to the varying angles of the skeletal system to envelop the entire body.
If a "topological knot" forms congenitally between the dermal layers and among the hair shafts in the human body, this knot, being a fixed structure, will not absorb forces according to the laws of physics but will instead reflect them onto the surrounding tissue. Naturally, this phenomenon depends on various factors such as the individual's growth rate, hair density, and the location and number of knots present.
In this study, through a reverse-analytic approach similar to reverse engineering, the existing development process of Frontal Fibrosing Alopecia has been systematically recorded. By identifying the directions of tension field lines in the skin and scalp, the presence of a topological knot in the hair whorl region was inferred. Consequently, in response to healthcare professionals who have stated that such a condition does not exist in the literature, the documentation of this study was initiated.
HTH Framework: An Intuitive and Simple Explanation
The scalp is defined as a dynamic region.
Hair strands are conceptualized as mechanical vectors.
Fixed structures such as hair whorls or nevi that contain hair strands and have extensionsinto the dermis are considered topologically invariant.
In a dynamic system, a topologically invariant represents a region that remains unchangeddespite the dynamism of the environment.
The inability of a dynamic system to change a constant does not render it in effective.
A topologically invariant does not absorb microforces; due to the limited elasticity andtension of the skin, these forces are reflected back to the tissue (via the angle of reflection and other indirectly affecting forces).
With growth, cranial expansion, and active hair follicle development, these topologicalinvariants create topological subnodes in the region, creating subtle but effective vector forces and cranial angle changes.
A topological node covers a region containing skin from various lateral angles.
When a new hair follicle appears, the combined effect of growth and inclination causes thisarea to shift; the hair follicles effectively fixes itself and the area.
This phenomenon is not limited to a single area; hair follicles in different areas show similar reactions due to local evolution.
Since these formations cannot be observed directly from the surface and the area exerts aspring-like force through lateral and micro-tensions, they can be mistakenly interpreted as autoimmune diseases.
Under the influence of this force, the hair follicles remain active but can only grow to acertain extent due to mechanical pressure (which may lead to the impression that the follicles have stopped growing for a different reason).
Similarly, these pressures and mechanical forces contribute to the fixation of the structureby compressing the follicles.
Over time, the topological nodal region begins to affect the skin morphology at the limitsof micro-movements and tissue tension.
Initially, other areas of the scalp are affected.
Within the topological node, these regions act as carriers for the skin; the microfoldssurrounding the epidermis always exert a mechanical traction force at approximately the midpoint of the hair shaft.
In certain areas, especially where the force collides with the bone tissue and the folliclesreach the epidermis, secondary topological nodes are formed connected to the primary node.
As these topological nodal structures evolve in their dynamic environment, they graduallylead to morphological disorders.
During growth, this process can be thought of as topological nodes that fix the epidermisat certain points and stabilize it continuously and increasingly at these places.
As a result, epidermal layers with micro-angle differences that are fixed at certain pointsemerge.
If the follicles are partially or completely unable to participate in this cycle - for examplearound the eyes - the tension that occurs, combined with the curvature of the region, causes the force to shift posteriorly and accumulate behind the eye.
The edges of the nose and lips (usually the concave angles of the facial bones) eventuallybecome areas where epidermal accumulation occurs.
Epidermal accumulation provides limited analytic continuity (human skin is generallyflexible, but at the limit of tension, multidirectional micromechanical forces find the closest path). Depending on the area: in some areas this results in a very thin and inelastic skin, while in others where it has the ability to be reoriented (such as the cheek area) it can cause a kind of inversion of the dermis.
The submental region is anatomically a complex structure composed of multiple layers ofsoft tissue. Its concave morphology, particularly between the inferior border of the mandible and the neck, predisposes certain points to the accumulation of mechanical tension. As a result of this concavity, increased tension and interstitial pressure may cause chronic mechanical compression of the thyroid gland. Such persistent mechanical stress can adversely affect the physiological functions of the thyroid gland and potentially lead to functional disorders.
The process by which these topological nodes transmit and distribute mechanical stressesis not limited to the scalp; it can have complex and systemic consequences affecting the entire body. Considering that the propagation of mechanical forces occurs through the subcutaneous connective tissue network, cascade effects can also occur in tissues in other parts of the body.
The continuous stress caused by mechanical forces in the subcutaneous tissues reachesdeeper tissues through interstitial structures and analytic continuity. In this case, connective tissue and fascia layers mediate the systemic transmission of mechanical stress, creating loads and pressure points on the musculoskeletal system, which can lead to chronic pain, postural disorders and movement restrictions.
Continuous mechanical stress can lead to changes in microvascular circulation andchronic low-grade inflammatory conditions. This causes the immune system to become overactive. In theory, it can also lead to changes in vascular morphology in later times.
Mechanical stress combined with induced inflammation causes the immune system tomisdirect its attack on normal tissues (because the direction of the force remains constant within its field).
The long-term effects of chronic stress can restrict the regional oxygen and nutrientsupply to the skin and underlying tissues, leading to permanent changes such as tissue fibrosis and sclerosis. This may provide a physical basis for the clinical presentation of connective tissue diseases and various skin conditions.
The lymphatic system will respond appropriately to mechanical forces. Although thismechanical action originates from the body itself, since it is very slow and subtle in its movements, the rate of response will be similarly slow. This may be why some types of lymphoma progress so slowly.
Over time, a body that is constantly under autoimmune attack, especially in areas that areunder the greatest stress and are affected by environmental factors, immunosuppression, or surgery, can develop mutations and cancer.
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