Every year, we spend billions of dollars of the world's limited resources on hair transplants, autoimmune disease research, cancers with unknown causes, and studies related to the pharmaceutical industry.

If we ignore or do not take into account a situation that can be simply explained from a different perspective, much of this resources can be misdirected.

Of course, in addition to this, there is the pain, financial loss, and psychological distress that people experience due to these diseases.

Before technology became so advanced, researchers would often present their reports through observation and often with a holistic approach [1] , [2] . (this area will be expanded)

However, with technological advances and discoveries such as the structure of DNA, we have begun to focus more on the idea that diseases that we cannot explain may be caused by DNA or autoimmune systems.

Perhaps it would be useful to take another look at the works of the great masters of the past.

The aim of creating this website is to offer a different and innovative perspective that goes beyond the current understanding of autoimmune diseases.

Since 2020, I have been working on this hypothesis independently and voluntarily, without receiving any financial support. I started my research with Frontal Fibrosing Alopecia and during this process, I discovered a topological knot on the scalp. By following the tension zones, soft areas and patterns on the skin, I found this multi-layered topological knot formed by the hair strands holding each other and the skin at small angles.

I searched for such a condition in the medical literature and could not find any information about it. This led me to the following thought: If this condition is not described in the literature, many related disorders can be misdiagnosed or not diagnosed at all.

This discovery led me to further deepen my research. Since 2020, I have devoted a significant part of my life to studying the characteristic features of diseases, their comorbidities and geometric structures. As a result of all these studies, I have developed a new hypothesis that does not exclude the existing theory that the autoimmune system attacks itself due to a faulty signal, but also includes the mechanical stress factor. For the sake of clarity and simplicity, I named this hypothesis "The Human Topological Hypothesis".

What If Our HaIr Strands Were Metal?

A Thought Experiment: "What If Our Hair Strands Were Metal?"

Let’s do an interesting analogy: Imagine that instead of hair, people naturally grew copper or aluminum wires with the same geometric structure—pointed at the ends and thicker towards the root.

In such a scenario, we would probably recognize the potential risks of these structures even before any hypothesis was needed. After all, copper has a tensile strength of 210–480 MPa and aluminum ranges from 70–600 MPa—almost identical to the average tensile strength of a human hair strand, which is 200–260 MPa! On top of that, the sharp-ended metal wires would likely create mechanical stress on the skin, with unpredictable consequences.

However, because we have always considered our hair strands to be "innocent" and "harmless" since birth, this possibility never even crossed our minds. Perhaps what we have overlooked is the combined effect of geometry and material properties.

Let’s consider structures that exist from birth, such as hair whorls and nevi. These can include hair strands and are known to extend into the dermis. If we imagined these structures made not of hair, but of metal wires (like copper or aluminum), we could have predicted from the outset how such features might morphologically affect the human body. This is because our skin is adaptive; even though its physical characteristics change throughout life, it has evolved to protect our body and will adapt to any persistent structure it encounters. This adaptability also applies to multi-angled micro-mechanical forces. It could have been foreseen that the forces exerted by hair strands—or even just a few hair strands—might, as we age, create a kind of chaos within the analytic continuity of the skin and body.

Why Does This Matter?

This analogy invites us to question traditional perspectives on the origins of diseases. Sometimes, what we think we know may actually hide a much more complex dynamic.

Key Takeaways:

• Collagen realigns dynamically under tension.

• Skin strength varies by direction (anisotropy).

• Langer’s lines guide surgical practices.

• Anatomical continuity exists between the forehead, temple, and scalp tissue layers.

• Human hair has an average tensile strength of 200–260 MPa, which is comparable to metals such as structural aluminum alloys (e.g., 2014-T6 aluminum: ~414 MPa), annealed copper (~210 MPa), and some grades of carbon steel (e.g., Q195: ~260 MPa)

[1] Findlay, G. H., & Harris, W. F. (1977). The topology of hair streams and whorls in man, with an observation on their relationship to epidermal ridge patterns. American Journal of Physical Anthropology, 46(3), 427–437.https://doi.org/10.1002/ajpa.1330460308

[2] Voigt, C. A. (1857). Über die Richtung der Haare am menschlichen Körper. Denkschriften der Kaiserlichen Akademie der Wissenschaften in Wien, 13, 1–35. OUCI

[3] Yang, W., Yu, Y., Ritchie, R. O., & Meyers, M. A. (2020). On the strength of hair across species. Matter, 2(1), 136–149. https://doi.org/10.1016/j.matt.2019.09.019

[4] Sharma, A., Singh, D., Kashyap, D., Kumar, S., Chamola, S., & Gupta, S. (2017). Analysis of fibre reinforced concrete: Using human hair as a fibre reinforcement. International Journal of Recent Scientific Research, 8(4), 16715–16720. https://doi.org/10.24327/ijrsr.2017.0804.0201

[5] Witte, M., Rubhausen, M., Jaspers, S., et al. (2021). A method to analyze the influence of mechanical strain on dermal collagen morphologies. Scientific Reports, 11, 7565. https://doi.org/10.1038/s41598-021-86907-7

[6] Liang, X., & Boppart, S. A. (2010). Biomechanical properties of in vivo human skin… IEEE Transactions on Biomedical Engineering, 57(4), 953–959. https://doi.org/10.1109/TBME.2009.2033464

[7] Ingallina, F., Alfertshofer, M. G., Schelke, L., Velthuis, P. J., Frank, K., Mardini, S., Millesi, E., Ehrl, D., Green, J. B., & Cotofana, S. (2022). The fascias of the forehead and temple aligned An anatomic narrative review. Facial Plastic Surgery Clinics of North America, 30(2), 215–224. https://doi.org/10.1016/j.fsc.2022.01.006